TY - JOUR
KW - Ophthalmology
AU - Rathinam S
AU - Parikh J
AU - Rao N
AB - Episcleritis, scleritis, and anterior uveitis are common clinical manifestations of ocular leprosy. Erythema nodosum leprosum (ENL) is an acute, exaggerated systemic immunological reaction that complicates the course of this chronic indolent disease. We present an ocular immunohistochemical study of severe form of ENL involving even the ciliary body and choroid resulting in the perforation of the globe on the initiation of anti leprosy therapy. We used CD-3, CD-68, S-100, and CD-20 for immunohistochemistry. It revealed plenty of CD-3-positive T-cells and CD-68-positive macrophages and a few S-100 and CD-20-positive cells. The inflammatory exudates stained positive for IgG and IgM. The diagnosis was ocular ENL.
BT - Indian Journal of Ophthalmology
DO - 10.4103/ijo.ijo_549_20
IS - 9
LA - eng
N2 - Episcleritis, scleritis, and anterior uveitis are common clinical manifestations of ocular leprosy. Erythema nodosum leprosum (ENL) is an acute, exaggerated systemic immunological reaction that complicates the course of this chronic indolent disease. We present an ocular immunohistochemical study of severe form of ENL involving even the ciliary body and choroid resulting in the perforation of the globe on the initiation of anti leprosy therapy. We used CD-3, CD-68, S-100, and CD-20 for immunohistochemistry. It revealed plenty of CD-3-positive T-cells and CD-68-positive macrophages and a few S-100 and CD-20-positive cells. The inflammatory exudates stained positive for IgG and IgM. The diagnosis was ocular ENL.
PB - Medknow
PY - 2020
EP - 2028
T2 - Indian Journal of Ophthalmology
TI - Ocular erythema nodosum leprosum: An immunohistochemical study
UR - http://www.ijo.in/temp/IndianJOphthalmol6892028-5794891_160548.pdf
VL - 68
SN - 0301-4738
ER -