01234nas a2200133 4500000000100000008004100001260002600042100001500068700001200083700001200095245002900107856005000136520091400186 2020 d bStatPearls Publishing1 aBhandari J1 aAwais M1 aGupta V00aLeprosy (Hansen Disease) uhttps://www.ncbi.nlm.nih.gov/books/NBK559307/3 aLeprosy is also referred to as Hansen disease. It is a chronic granulomatous infection generally caused by Mycobacterium leprae and Mycobacterium lepromatosis, both of which primarily affects the skin and peripheral nerves. "Mycobacterium leprae complex" comprises M. leprae and M. lepromatosis. Though both mycobacteria are classified as different species because of there DNA sequences, they both are obligate intracellular organisms and have many similar features causing the same clinical disease. Leprosy is of great concern in the medical community. This disease is not highly contagious, contrary to belief, and treatment is readily available for this ailment. Through awareness and early medical intervention, significant reduction causing disability in the eyes, hands, and feet is possible. Relapses tend to be rare, but any damage caused by neuropathy is irreversible and may require lifelong care.