01451nas a2200169 4500000000100000008004100001100001400042700001800056700001300074700001600087700001400103245010800117856005100225300001200276490000700288520098600295 2020 d 1 aDarlong J 1 aGovindharaj P 1 aMahato B 1 aLockwood DN 1 aWalker SL 00 aHealth-related quality of life associated with erythema nodosum leprosum in Purulia, West Bengal, India uhttps://leprosyreview.org/article/91/1/19-0047 a100-107 0 v91 3 aObjectives:
To determine the impact of erythema nodosum leprosum (ENL) on health-related quality of life (HRQoL) of persons affected by leprosy compared to individuals without ENL using the Medical Outcomes Study: 36-Item Short Form Survey (SF-36).
Methods:
Individuals with a diagnosis of leprosy completed the Bengali version of the SF-36. The responses to the items of the surveys were coded, summed and transformed into a score for each of the eight domains. A lower score reflects a worse HRQoL.
Results:
290 individuals with a median age of 32 years (Range 14–82) participated. Individuals with ENL and those with isolated neuritis had significantly lower mean scores in all domains compared with individuals without reaction or neuritis except the domain of physical functioning in those with ENL.
Conclusions:
This study demonstrates an association of reduced HRQoL with ENL compared to individuals without reaction or neuritis.