00952nas a2200121 4500000000100000008004100001260003800042100001400080245003400094250002700128856008000155520059500235 2020 d bInternational textbook of leprosy1 aLambert S00aImmunosuppression and Leprosy aScollard DM, Gillis TP uhttps://m3u9w4p9.stackpathcdn.com/sites/default/files/ITL_3_3%20FINAL_0.pdf3 aThis chapter discusses the presentation and management of leprosy in an immunosuppressed host. An immunocompromised host is a patient who does not have the ability to respond normally to an infection due to an impaired or weakened immune system. Immunodeficiency may be inherited (e.g., hypogammaglobulinemia) or acquired as a result of certain conditions such as HIV/AIDS, some cancers, malnutrition, diabetes, splenectomy, and trauma. Many drugs will also cause immunosuppression: chemotherapy, corticosteroids, and immunosuppressants used in organ transplants or autoimmune diseases.