01101nas a2200145   4500000000100000008004100001100001300042700001200055700001200067245007800079856006900157300001100226490000700237520071100244       2020                            d1 aKanwar P1 aGupta J1 aSingh S00aLeprosy with psychosis and neuroleptic malignant syndrome : A case report  uhttp://www.ijl.org.in/2020/06%20P%20Kanwar%20et%20al%2049-47.pdf  a 49-510 v923 aLeprosy has been associated with increased prevalence of psychiatric comorbidities. Acute Polymorphic
Psychotic Disorder (APPD) is one of severe psychiatric disorders which is characterized by delusions,
hallucinations and lack of insight. Rarely, treatment of APPD with antipsychotics leads to development of
Neuroleptic Malignant Syndrome (NMS) which is an idiosyncratic, life threatening complication of treatment
with antipsychotic drugs. We report here a case of NMS in a patient of leprosy who was taking Multibacillary
regimen (MDT-MB) for 1year before onset of APPD and developed NMS on treatment with Haloperidol.
Patient was successfully managed with supportive measures and Bromocriptine.