01252nas a2200241 4500000000100000008004100001260001200042653002700054653001700081653000800098653002200106653001200128653001200140100001400152700001600166700001400182700001400196700001200210245008600222300001900308520066900327022001400996 2019 d c11/201910aLate reversal reaction10aLive bacilli10aMDT10aResistant bacilli10arelapse10asteroid1 aSardana K1 aMathachan S1 aAgrawal D1 aLavania M1 aAhuja M00aLate reversal reaction with resistant Mycobacterium leprae: an emerging paradigm. a494755198844213 a

While Type 1 reaction is seen in leprosy patients, in up to 30% of patients, late reaction is uncommon and usually is seen in the first two years of release from treatment (RFT). It is believed that these reactions are consequent to dead bacilli and the World Health Organization recommends treatment with steroids without multidrug therapy (MDT; with the proviso of adding clofazimine only when steroid therapy exceeds four months duration). A few studies, though, have noted live bacilli present in reversal reactions and hence recommend concomitant MDT. We report a case of resistant bacilli in late reaction and discuss the implications of this finding.

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